GALLERY FIFTY ONE is specialized in fine art photography: vintage, classic, fashion, African and contemporary photography. From June 2000, the gallery is the only major art gallery in Belgium devoted exclusively to fine art photography. The gallery deals with young emerging photographers and established photographers of the 20th and 21st century.

Since 2009, the gallery also started a New York office to meet the growing demands of American clients and since 2011, the gallery started a dialogue between photography and works on paper. Regularly, these exhibitions are conducted to emphasize the artistic gaze of photography.