In 1981 Frank Demaegd and his wife opened Zeno X Gallery and started showing the work of architects like John Körmeling and Rem Koolhaas.
Later on the gallery began to work with artists like Anne-Mie Van Kerckhoven and Patrick Van Caeckenbergh. With those artists, Zeno X became the subject of international discussion. In 1988 Raoul De Keyser showed for the first time at the gallery and in 1990 Luc Tuymans was presented. Marlene Dumas joined in 1991 and Mark Manders' first solo show in Antwerp took place at Zeno X Gallery in 1994.
Recently Zeno X has started working with Grace Schwindt, Susan Hartnett, Pietro Roccasava and Mircea Suciu. In over 30 years Zeno X put together more than 180 exhibitions and attended more than 80 art fairs.